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8-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: St Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Departs: Sat. 9/5/26     Returns: Sun. 9/13/26     Nights: 8
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2025 Departures: 10/4, 10/11, 10/17, 10/18, 10/24, 11/1, 11/9, 11/10, 11/17
2026 Departures: 2/14, 2/21, 2/28, 3/7, 3/14, 3/21, 3/28, 4/4, 4/11, 4/18, 4/25, 5/2, 5/9, 5/16, 5/23, 5/30, 6/6, 7/4, 7/11, 7/18, 7/25, 8/1, 8/8, 8/15, 8/22, 8/29, 9/12, 9/19, 10/3, 10/10, 10/16, 10/17, 10/23, 10/31
2027 Departures: 2/13, 2/20, 2/27, 3/6, 3/13, 3/20, 3/27, 4/3, 4/10, 4/17, 4/24, 5/1, 5/8, 5/15, 5/22, 5/29, 6/5, 7/3, 7/10, 7/17, 7/24, 7/31, 8/7, 8/14, 8/21, 8/28, 9/4, 9/11, 9/18, 10/29, 11/4, 11/10, 11/17, 11/24, 12/1, 12/8, 12/15, 12/22, 12/22, 12/28, 12/29
American Cruise Lines
 


8-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: Minneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)
Departs: Sat. 9/12/26     Returns: Sun. 9/20/26     Nights: 8
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2025 Departures: 10/4, 10/11, 10/17, 10/18, 10/24, 11/1, 11/9, 11/10, 11/17
2026 Departures: 2/14, 2/21, 2/28, 3/7, 3/14, 3/21, 3/28, 4/4, 4/11, 4/18, 4/25, 5/2, 5/9, 5/16, 5/23, 5/30, 6/6, 7/4, 7/11, 7/18, 7/25, 8/1, 8/8, 8/15, 8/22, 8/29, 9/5, 9/19, 10/3, 10/10, 10/16, 10/17, 10/23, 10/31
2027 Departures: 2/13, 2/20, 2/27, 3/6, 3/13, 3/20, 3/27, 4/3, 4/10, 4/17, 4/24, 5/1, 5/8, 5/15, 5/22, 5/29, 6/5, 7/3, 7/10, 7/17, 7/24, 7/31, 8/7, 8/14, 8/21, 8/28, 9/4, 9/11, 9/18, 10/29, 11/4, 11/10, 11/17, 11/24, 12/1, 12/8, 12/15, 12/22, 12/22, 12/28, 12/29
American Cruise Lines
 


14-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: Minneapolis/St. Paul, Red Wing, La Crosse, Dubuque, Davenport, Fort Madison, Hannibal, St Louis, Mississippi River, Memphis, Mississippi River, Vicksburg, Natchez, Baton Rouge, New Orleans
Departs: Sat. 9/12/26     Returns: Sat. 9/26/26     Nights: 14
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2026 Departures: 8/15
American Cruise Lines
 


8-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: St Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Departs: Sat. 9/19/26     Returns: Sun. 9/27/26     Nights: 8
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2025 Departures: 10/4, 10/11, 10/17, 10/18, 10/24, 11/1, 11/9, 11/10, 11/17
2026 Departures: 2/14, 2/21, 2/28, 3/7, 3/14, 3/21, 3/28, 4/4, 4/11, 4/18, 4/25, 5/2, 5/9, 5/16, 5/23, 5/30, 6/6, 7/4, 7/11, 7/18, 7/25, 8/1, 8/8, 8/15, 8/22, 8/29, 9/5, 9/12, 10/3, 10/10, 10/16, 10/17, 10/23, 10/31
2027 Departures: 2/13, 2/20, 2/27, 3/6, 3/13, 3/20, 3/27, 4/3, 4/10, 4/17, 4/24, 5/1, 5/8, 5/15, 5/22, 5/29, 6/5, 7/3, 7/10, 7/17, 7/24, 7/31, 8/7, 8/14, 8/21, 8/28, 9/4, 9/11, 9/18, 10/29, 11/4, 11/10, 11/17, 11/24, 12/1, 12/8, 12/15, 12/22, 12/22, 12/28, 12/29
American Cruise Lines
 


7-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: New Orleans, Oak Alley, Baton Rouge, St. Francisville, Natchez, Vicksburg, Mississippi River, Memphis
Departs: Sat. 9/26/26     Returns: Sat. 10/3/26     Nights: 7
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2025 Departures: 10/25, 11/14, 11/20, 11/26, 12/2
2026 Departures: 10/24
American Cruise Lines
 


15-Night North American Waterways (U.S. Rivers)

American_Serenade
Cruise Line: American Cruise Lines    Ship: American Serenade
Ports of Call: Minneapolis/St. Paul, Mississippi River, La Crosse, Dubuque, Davenport, Cruising the River, Hannibal, Cruising the River, St Louis, Memphis, Tunica, Cruising the River, Vicksburg, Natchez, Baton Rouge, New Orleans
Departs: Sat. 9/26/26     Returns: Sun. 10/11/26     Nights: 15
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade... expand Expand
Additional Sailing Dates
2027 Departures: 9/25
American Cruise Lines
 


Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Government taxes and fees are additional. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.